Maya Gosztyla
Graduate Student (Ph.D.)
Biomedical Sciences
NSF Graduate Research Fellow; Myotonic Dystrophy Foundation Predoctoral Fellow
Summary
Maya received her B.S. in Neuroscience and Molecular Genetics from the Ohio State University. Her honors thesis in Dr. Mark Seeger’s lab focused on polymorphic variants influencing axon guidance in a fruit fly model. She also spent a summer at Dr. Johannes Graff’s lab in Switzerland researching neuronal hyperactivity in an Alzheimer’s disease. After graduating, Maya joined the National Center for Advancing Translational Sciences (NCATS) as an NIH Post-Baccalaureate Fellow, where she developed a high-throughput mass spectrometry-based assay to screen drug candidates for lipid storage diseases. Maya then moved to San Diego to join UCSD’s Biomedical Sciences Graduate Program. Her research in the Yeo lab focuses on developing RNA-targeted therapeutics for neurodegenerative diseases. In her free time, Maya enjoys hiking, cooking, and watching anime.
Education
B.S. Neuroscience and Molecular Genetics, The Ohio State University, 2018
Contact
mgosztyl@health.ucsd.edu
Publications
Morelli K. H., Wu Q., Gosztyla M. L., Liu H., Yao M., Zhang C., Chen J., Marina R. J., Lee K., Jones K. L., Huang M. Y., Li A., Smith-Geater C., Thompson L. M., Duan W., & Yeo G. W. (2023). An RNA-targeting CRISPR-Cas13d system alleviates disease-related phenotypes in Huntington’s disease models. Nature Neuroscience, 26(1), 27–38.
Qin Y., Huttlin E., Winsnes C., Gosztyla M. L., Wacheul L., Kelly M. R., Blue S. M., Zheng F., Chen M., Schaffer L. V., Licon K., Bäckström A., Vaites L. P., Lee J. J., Ouyang W., Liu S. N., Zhang T., Silva E., Park J., Pitea A., Kreisberg J. F., Gygi S. P., Ma J., Harper J. W., Yeo G. W., Lafontaine D. L., Lundberg E., Ideker T. (2021). A multi-scale map of cell structure fusing protein images and interactions. Nature 600, 536–542. https://doi.org/10.1038/s41586-021-04115-9
Gosztyla M. L., Kwong L., Murray N. A., Williams C. E., Behnke N., Curry P., Corbett K. D., DSouza K. N., Gala de Pablo J., Gicobi J., Javidnia M., Lotay N., Madison Prescott S., Quinn J. P., Rivera Z. M. G., Smith M. A., Tang K. T. Y., Venkat A., Yamoah M. A. (2021). Responses to 10 common criticisms of anti-racism action in STEMM. PLoS Computational Biology, 17(7): e1009141. doi:10.1371/journal.pcbi.1009141.
Wei Z., Fang Y., Gosztyla M. L., Li A., Huang W., LeClair C. A., Simeonov A., Tao D., Xia M. (2021). A direct peptide reactivity assay using a high-throughput mass spectrometry screening platform for detection of skin sensitizers. Toxicology Letters, 338, 67-77. doi:10.1016/j.toxlet.2020.12.002.
Roth J. S., Lee T. D., Cheff D. M., Gosztyla M. L., Asawa R., Danchik C., Michael S., Simeonov S., Klumpp-Thomas C., Wilson K., Hall M. D. (2020). Keeping it clean: the cell culture quality control experience at the National Center for Advancing Translational Sciences. SLAS Discovery, doi:10.1177/2472555220911451.
Baljinnyam B., Gosztyla M. L., Ronzetti M., Simeonov A., Coussens N. P. (2020). Application of Fluorescence Technologies to High-Throughput Screening Assays. Wigglesworth M, Murray D, Holdgate G, Blackett CJ (Eds.), High-Throughput Screening: Methods, Techniques and Applications. Hauppauge, NY: NOVA Science Publishers, Inc.
Gosztyla M. L. (2020). Nutrition and Alzheimer’s Disease. Jadavji NM (Ed.), The Role of Nutrition During Aging: A Handbook for Nutritional Neuroscience. London, UK: Brain & Life Publishing.
Gosztyla M. L., Brothers H. M., Robinson S. R. (2018). Alzheimer’s Amyloid-ß is an Antimicrobial Peptide: A Review of the Evidence. Journal of Alzheimer’s Disease, 62(4), 1495-1506.
Brothers H. M., Gosztyla M. L., Robinson SR (2018). The physiological roles of amyloid-ß peptide hint at new ways to treat Alzheimer’s disease. Frontiers in Aging Neuroscience, 10, 118.
Robinson S. R., Brothers H. M., Gosztyla M. L. (2018). Consequences of redefining Alzheimer’s disease in terms of amyloid burden without regard to cognitive impairment. Neural Regeneration Research, 13(12), 2098-2099.
