Krysten Jones
Staff Research Associate II
Cellular and Molecular Medicine
Summary
Krysten received both her bachelor’s and master’s in Biological Sciences at California Polytechnic (CalPoly) State University. At CalPoly, she worked in Dr. Sandra Clemet’s lab studying the mechanism of Tristetraprolin (TTP) mediated mRNA decay. Upon graduation, she joined the Yeo lab working under Ryan Marina studying Ataxin-2 involvement in Amyotrophic Lateral Sclerosis (ALS). Since then, she has worked on a variety of projects examining Autism Spectrum Disorder (ASD), Huntington’s Disease, Myotonic Dystrophy, COVID-19, and others.
Krysten is the primary technician for the Yeo lab’s COPACABANA (Collaboration on preclinical autism cellular assays, biosignatures, and network analysis) project. Under the direction of postdoc Josh Schwartz, she has generated isogenic CRISPR edited lines and optimized and implemented 2D and 3D neuronal differentiation protocols for over 70 independent lines modeling 10 different ASD subtypes. Krysten has recently been admitted to the Biomedical Sciences doctoral program at UCSD for Fall 2022.
Education
M.S. in Biological Sciences (Specialization in Regenerative Medicine), California Polytechnic State University, SLO 2019
B.S. in Biological Sciences, California Polytechnic State University, SLO 2014
Publications
Joshua L. Schwartz, Krysten L. Jones & Gene W. Yeo (2021) Repeat RNA expansion disorders of the nervous system: post-transcriptional mechanisms and therapeutic strategies, Critical Reviews in Biochemistry and Molecular Biology, 56:1, 31-53, DOI: 10.1080/10409238.2020.1841726