Katie Jing Kay Lam

Graduate Student

Biomedical Sciences

 

 

Summary

Katie is a Ph.D. student in the Biomedical Sciences program at UC San Diego. She received her B.S in Human Biology and M.S. in Biology from UC San Diego. As an undergraduate, she worked in Dr. Milton Saier’s lab, contributing to several bioinformatics projects in comparative genomics of transporter proteins. She continued her master’s thesis in the same lab, focusing on the transcriptional regulation in E. coli. After graduating, Katie joined Dr. Claire Clelland’s lab at UC San Francisco, where she worked on iPSC modeling of Alzheimer’s disease and CRISPR gene editing therapies for amyotrophic lateral sclerosis (ALS).

Outside of lab, Katie likes spending time with her four cats at home.

 

Education

B.S. Human Biology, UC San Diego, 2020

M.S. Biology, UC San Diego, 2022

 

Contact

kal103@health.ucsd.edu

Publications

  • Salomonsson S. E., Maltos A. M., Gill K., Aladesuyi Arogundade O., Brown K. A., Sachdev A., Sckaff M., Lam K. J. K., Fisher I. J., Chouhan R. S., Van Laar V. S., Marley C. B., McLaughlin I., Bankiewicz K. S., Tsai Y. C., Conklin B. R., Clelland C. D. Validated assays for the quantification of C9orf72 human pathology. Sci Rep. 2024 Jan 8;14(1):828. doi: 10.1038/s41598-023-50667-3.

  • Lam K. J. K., Zhang Z., Saier M. H. Histone-like nucleoid structuring (H-NS) protein silences the beta-glucoside (bgl) utilization operon in Escherichia coli by forming a DNA loop. Comput Struct Biotechnol J. 2022 Nov 12;20:6287-6301. doi: 10.1016/j.csbj.2022.11.027.

  • Tran D., Zhang Z., Lam K. J. K., Saier M. H. Jr. Effects of Global and Specific DNA-Binding Proteins on Transcriptional Regulation of the E. coli bgl Operon. Int J Mol Sci. 2022 Sep 7;23(18):10343. doi: 10.3390/ijms231810343.

  • Russum S., Lam K. J. K., Wong N. A., Iddamsetty V., Hendargo K. J., Wang J., Dubey A., Zhang Y., Medrano-Soto A., Saier M. H. Jr. Comparative population genomic analyses of transporters within the Asgard archaeal superphylum. PLoS One. 2021 Mar 26;16(3):e0247806. doi: 10.1371/journal.pone.0247806.

  • Saier M. H., Reddy V. S., Moreno-Hagelsieb G., Hendargo K. J., Zhang Y., Iddamsetty V., Lam K. J. K., Tian N., Russum S., Wang J., Medrano-Soto A. The Transporter Classification Database (TCDB): 2021 update. Nucleic Acids Res. 2021 Jan 8;49(D1):D461-D467. doi: 10.1093/nar/gkaa1004.

  • Wang S. C., Davejan P., Hendargo K. J., Javadi-Razaz I., Chou A., Yee D. C., Ghazi F., Lam K. J. K., Conn A. M., Madrigal A., Medrano-Soto A., Saier M. H. Jr. Expansion of the Major Facilitator Superfamily (MFS) to include novel transporters as well as transmembrane-acting enzymes. Biochim Biophys Acta Biomembr. 2020 Sep 1;1862(9):183277. doi: 10.1016/j.bbamem.2020.183277.