En-Ching Luo
Graduate Student (Ph.D.) Alumni
Bioengineering
Taiwanese Government Fellow
Summary
En-Ching Luo received her master’s degree in Physiology from National Taiwan University. In her master’s studies, she worked in a bioinformatics and biostatistics core laboratory. Her master’s thesis focused on microRNA regulation of breast cancer. Before starting her graduate studies in Bioengineering at UC San Diego, Enching was a research assistance in a biomaterial laboratory at National Tsing Hua University. She constructed a mouse model of metastatic colon cancer to study drug delivery. As a bioengineering graduate student at UCSD, Enching is interested in RNA regulation and genomics. Enching is funded by the Taiwanese government.
Education
M.S. National Taiwan University, Taiwan 2014
B.S. National Tsing Hua University, Taiwan 2011
Contact
e1luo at ucsd.edu
Publications
Luo EC, Nathanson JL, Tan FE, Schwartz JL, Schmok JC, Shankar A, Markmiller S, Yee BA, Sathe S, Pratt GA, Scaletta DB, Ha Y, Hill DE, Aigner S, Yeo GW. Large-scale tethered function assays identify factors that regulate mRNA stability and translation. Nature Structural and Molecular Biology. 2020.
Coyne A, Zaepfel B, Hayes L, Fitchman B, Salzberg Y, Luo EC, Bowen K, Trost H, Aigner S, Rigo F, Yeo GW, Harel A, Svendsen CN, Sareen D, Rothstein JD. G4C2 Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD. Neuron. 2020
Di Stefano B§, Luo EC§, Haggerty C, Aigner S, Charlton J, Brumbaugh J, Ji F, Rabano Jiménez I, Clowers KJ, Huebner AJ, Clement K, Lipchina I, de Kort MAC, Anselmo A, Pulice J, Gerli MFM, Gu H, Gygi SP, Sadreyev RI, Meissner A, Yeo GW, Hochedlinger K. The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis. Cell Stem Cell. 2019 Sep 27. doi:10.1016/j.stem.2019.08.018. (§ Co-first authors)
Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, Bennett EJ, Lécuyer E, Yeo GW. Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell. 2018 Jan 25. doi:10.1016/j.cell.2017.12.032
Luo EC, Chang YC, Sher YP, Huang WY, Chuang LL, Chiu YC, Tsai MH, Chuang EY, Lai LC. MicroRNA-769-3p down-regulates NDRG1 and enhances apoptosis in MCF-7 cells during reoxygenation. Sci Rep. 2014 Aug 1. doi: 10.1038/srep05908.
Liu YJ, Lin YF, Chen YF, Luo EC, Sher YP, Tsai MH, Chuang EY, Lai LC. MicroRNA-449a enhances radiosensitivity in CL1-0 lung adenocarcinoma cells. PLoS One. 2013 Apr 17. doi: 10.1371/journal.pone.0062383.