Anthony Vu

Graduate Student (Ph.D.)

Biomedical Sciences

ARCS Fellow

 

 

Summary

Anthony Vu received his B.S. in Biochemistry: Cell Biology from the UCSD in 2008. He earned his M.S. degree a year later from UCSD working in Dr. Fred H. Gage’s lab at the Salk Institute for Biological Studies where he characterized the nuclear and cytoplasmic roles of the transcription factor REST in hESC and hESC derived human NPCs. Currently, as a staff associate in Dr. Gene Yeo’s lab, Anthony works on investigating the roles of RNA binding proteins in neurodegenerative diseases using human iPSCs.

 

Education

Ph.D., Biomedical Sciences, University of California, San Diego, 2023

M.S., Biology, University of California, San Diego, 2009

B.S., Biochemistry: Cell Biology, University of California, San Diego, 2008

 

Contact

aqvu@ucsd.edu

Publications

  • Begovich K., Vu A. Q., Yeo G. W., Wilhelm J. E. J Cell Biol, 2020. Conserved metabolite regulation of stress granule assembly via AdoMet.

  • Wheeler E. C. §, Vu A. Q. §, Einstein J. M., DiSalvo M., Ahmed N., Van Nostrand E. L., Shiskin A. A., Jin W., Allbritton N. L., Yeo G.W. Nature Methods, 2020. (§ co-first author). Pooled CRISPR screens with ima-based phenotyping on microRaft arrays reveals stress granule-regulatory factors.

  • Fang M. Y., Markmiller S., Vu A. Q., Javaherian A., Dowdle W. E., Jolivet P., Bushway P. J., Castello N. A., Baral A., Chan M. Y., Linsley J. W., Linsley D., Mercola M., Finkbeiner S., Lecuyer E., Lewcock J. W., Yeo G. W. Neuron, 2019. Small-molecule modulation of TDP-43 recruitment to stress granules prevents persistent TDP-43 accumulation in ALS/FTD.

  • Gould T. W., Dominguez B., de Winter F., Yeo G. W., Liu P., Sundararaman B., Stark T., Vu A, Q., Degen J. L., Lin W., Lee K. F. PLoS Genet, 2019.Glial cells maintain synapses by inhibiting an activity-dependent retrograde protease signal.

  • Krach F., Batra R., Wheeler E. C., Vu A. Q., Wang R., Hutt K., Rabin S. J., Baughn M. W., Libby R. T., Diaz‑Garcia S., Stauffer J., Pirie E., Saberi S., Rodriguez M., Madrigal A. A., Kohl Z., Winner B., Yeo G. W., Ravits J. Acta Neuropathologica, 2018. Transcriptome–pathology correlation identifies interplay between TDP‑43 and the expression of its kinase CK1E in sporadic ALS. [PDF]

  • Kapeli K., Pratt G. A., Vu A. Q., Hutt K. R., Martinez F. J., Sundararaman B., Batra R., Freese P., Lambert N. J., Huelga S. C., Chun S. J., Liang T. Y., Chang J., Donohue J. P., Shiue L., Zhang J., Zhu H., Cambi F., Kasarskis E., Hoon S., Ares M. Jr., Burge C. B., Ravits J., Rigo F., Yeo G. W. Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses. Nat Commun. 2016.

  • Siddiqi S., Nee Foo J., Vu A. Q., Saad A., Silver D. L., Mansoor A., Hong Tay S. K., Abbasi S., Hashmi A. H., Janjua J., Khalid S., Tai E. S., Yeo G. W., Khor C. C.A novel splice-site mutation in ALS2 establishes the diagnosis of juvenile amyotrophic lateral sclerosis in a family with early onset anarthria and generalized dystonias. PLoS One. 2014.

  • Lagier-Tourenne C., Polymenidou M., Hutt K. R., Vu A. Q., Baughn M., Huelga S. C., Clutario K. M., Ling S. C., Liang T. Y., Mazur C., Wancewicz E., Kim A. S., Watt A., Freier S., Hicks G. G., Donohue J. P., Shiue L., Bennett C.F., Ravits J., Cleveland D. W., & Yeo G. W. Nature Neuroscience, 2012. Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs. [PDF]

  • Wilbert M. W., Huelga S. C., Kapeli K., Stark T. J., Liang T. Y., Chen S. X., Yan B. Y., Nathanson J. L., Hutt K. R., Lovci M. T., Kazan H., Vu A. Q., Massirer K. B., Morris Q., Hoon S., Yeo G. W. Molecular Cell, 2012. LIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundance. [Mol Cell]

  • Huelga S. C., Vu A. Q., Arnold J. D., Liang T. Y., Liu P. P., Yan B. Y., Donohue J. P., Shiue L., Hoon S., Brenner S., Ares M., Yeo G. W. Cell Reports. 2012 Integrative Genome-wide Analysis reveals cooperative regulation of Alternative Splicing by hnRNP Proteins. [Open Access]