Anne Conway Gable

Graduate Student (Ph.D.) Alumni

Biomedical Sciences

 

 

Summary

Boyko is a Ph.D. student in the Bioinformatics and Systems Biology program at University of California, San Diego. His research interests lie at the intersection of machine learning and molecular biology. Boyko’s scientific career started in Prof. Daphne Koller’s group at the Stanford Artificial Intelligence Lab where he helped create HACO, a clustering algorithm which integrates multiple sources of noisy experimental data to exactly reconstruct protein complexes and their interactions. Since this debut, he has been involved in several other projects: * an automated microscopy system for tracking and lineage reconstruction of pluripotent stem cells developed with Professors Sebastian Thrun and Helen Blau at Stanford University * Hammer, a tool for error correction of high-throughput sequencing datasets developed by Paul Medvedev and Prof. Pavel Pevzner at UC San Diego RobustPSI, an investigation into the challenges of estimating percent inclusion for alternatively spliced junctions from RNA-seq data conducted with Prof. Brendan Frey at the University of Toronto.

 

Education

B.S., Biology and Music, Emory University, 2008

 

Contact

Publications

  • Kim Y, Deshpande A, Dai Y, Kim JJ, Lindgren A, Conway A, Clark AT, Wong DT. Cyclin-dependent kinase 2-associating protein 1 Commits Murine Embryonic Stem Cell Differentiation through Retinoblastoma Protein Regulation. J Biol Chem. June 2009. Epub ahead of print.

  • Park TS, Galic Z, Conway AE, Lindgren A, van Handel BJ, Magnusson M, Richter L, Teitell MA, Mikkola HK, Lowry WE, Plath K, Clark AT. Derivation of primordial germ cells from human embryonic and induced pluripotent stem cells is significantly improved by coculture with human fetal gonadal cells. Stem Cells. April 2009.

  • Karumbayaram S, Novitch BG, Patterson M, Umbach JA, Richter L, Lindgren A, Conway AE, Clark AT, Goldman SA, Plath K, Wiedau-Pazos M, Kornblum HI, Lowry WE. Directed differentiation of human-induced pluripotent stem cells generates active motor neurons. Stem Cells. April 2009.

  • Xie W, Song C, Young NL, Sperling AS, Xu F, Sridharan R, Conway AE, Garcia BA, Plath K, Clark AT, Grunstein M. Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells. Molecular Cell. February 2009.

  • Conway, AE., Lindgren, A., Galic, Z., Pyle, D., Wu, H., Zack, J., Pelligrini, M., Teitell, MA., Clark, AT. A self-renewal program controls the expansion of genetically unstable cancer stem cells in pluripotent stem cell-derived tumors. Stem Cells. January 2009.